Molecular Characterization of Genetic and Epigenetic Alterations in Gliomas

<p>Glioma development and progression are driven by complex genetic alterations, including point mutations and gain or loss of genomic copy number, as well as epigenetic aberrations, including DNA methylation and histone modifications. However, the molecular mechanisms underlying the causes a...

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Bibliographic Details
Main Author: Duncan, Christopher Gentry
Other Authors: Yan, Hai
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10161/6115