Involvement of a DNA Polymerase III Subunit in the Bacterial Response to Quinolones
<p>Quinolone treatment induces stabilized cleavage complexes (SCCs), consisting of a covalent gyrase-DNA complex, and processing of these complexes is thought to cause double-strand breaks and chromosome fragmentation. SCCs are required but not sufficient for cytotoxicity; the mechanism that c...
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2014
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| Online Access: | http://hdl.handle.net/10161/8773 |