The Role of Redox-dependent Reactions with Kras Cysteine 118 in Tumorigenesis
<p>The Ras family of small GTPases, comprised of the KRAS, NRAS, and HRAS genes, are mutated to encode constitutively-active, GTP-bound, oncogenic proteins in upwards of one quarter or more of all human cancers, which is well established to promote tumorigenesis. Despite the prominent role th...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
2015
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10161/9806 |