Nicotine-enhanced sign tracking results in greater cocaine demand in rats using a behavior economic analysis approach.

Rationale. Nicotine is often considered a ‘gateway’ drug because people typically experiment with tobacco before illicit drugs such as cocaine and amphetamine. We have shown that nicotine increases approach to reward-associated stimuli, this is referred to as ‘sign-tracking’, and that this effect pe...

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Bibliographic Details
Main Authors: Majors, Chloe T, Harryman, Dustin C, Smith, Amanda L, Day, Taylor C, Pham, Merlyn, Kosky, Madison M, Stillwell, Emily, Palmatier, Matthew
Published: Digital Commons @ East Tennessee State University 2019
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Online Access:https://dc.etsu.edu/asrf/2019/schedule/119