Attempted Synthesis of a Photoreactive Geranylcysteine Derivative.
In an attempt to synthesize a photoreactive geranylcysteine derivative, A, with an appropriate photoprobe to be studied as a mimic for farnesylated protein, B, the following syntheses were carried out. The hydroxyl group of geraniol was protected with DHP/PPTs to generate 1 (98.1%). Allylic oxidat...
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Digital Commons @ East Tennessee State University
2004
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Online Access: | https://dc.etsu.edu/etd/915 https://dc.etsu.edu/cgi/viewcontent.cgi?article=2072&context=etd |