A Novel Mode of Action of C-reactive Protein in Protecting Against Streptococcus pneumoniae Infection and Synergy with Antibiotics

A Novel Mode of Action of C-reactive Protein in Protecting Against Streptococcus pneumoniae Infection and Synergy with Antibiotics

C-reactive protein (CRP) is a part of the innate immune system, is synthesized in the liver, its blood level increases in inflammatory states, and it binds to Streptococcus pneumoniae. The conformation of CRP is altered under conditions mimicking an inflammatory milieu and this non-native CRP also b...

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Bibliographic Details
Main Author: Ngwa, Donald
Format: Others
Language:English
Published: Digital Commons @ East Tennessee State University 2020
Subjects:
C-reactive protein
Complement
Factor H
Phosphocholine
Pneumococcal C-polysaccharide
Streptococcus pneumoniae
Biochemistry
Molecular Biology
Pathogenic Microbiology
Online Access:https://dc.etsu.edu/etd/3752
https://dc.etsu.edu/cgi/viewcontent.cgi?article=5187&context=etd

Internet

https://dc.etsu.edu/etd/3752
https://dc.etsu.edu/cgi/viewcontent.cgi?article=5187&context=etd

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