Associations of Perfluoroalkyl Substances (PFASs) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK)

Background: Prenatal exposure to perfluoroalkyl substances (PFAS) has been associated with lower birth weight in epidemiologic studies. This association could be attributable to glomerular filtration rate (GFR), which is related to PFAS concentration and birth weight. Objectives: We used a physiolog...

Full description

Bibliographic Details
Main Authors: Verner, Marc-André, Loccisano, Anne E., Morken, Nils-Halvdan, Yoon, Miyoung, Wu, Huali, McDougall, Robin, Maisonet, Mildred, Marcus, Michele, Kishi, Reiko, Miyashita, Chihiro, Chen, Mei-Huei, Hsieh, Wu-Shiun, Andersen, Melvin E., Clewell, Harvey J., III, Longnecker, Matthew P.
Format: Others
Published: Digital Commons @ East Tennessee State University 2015
Subjects:
Online Access:https://dc.etsu.edu/etsu-works/28
https://dc.etsu.edu/cgi/viewcontent.cgi?article=1028&context=etsu-works