Transcription Factor Phox2 Upregulates Expression of Norepinephrine Transporter and Dopamine β-Hydroxylase in Adult Rat Brains

Transcription Factor Phox2 Upregulates Expression of Norepinephrine Transporter and Dopamine β-Hydroxylase in Adult Rat Brains

Degeneration of the noradrenergic locus coeruleus (LC) in aging and neurodegenerative diseases is well documented. Slowing or reversing this effect may have therapeutic implications. Phox2a and Phox2b are homeodomain transcriptional factors that function as determinants of the noradrenergic phenotyp...

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Bibliographic Details
Main Authors: Fan, Y., Huang, J., Duffourc, M., Kao, R. L., Ordway, G. A., Huang, R., Zhu, Meng Yang
Format: Others
Published: Digital Commons @ East Tennessee State University 2011
Subjects:
dopamine-β-hydroxylase
locus coeruleus
neurogenesis
noradrenergic neurons
norepinephrine transporter
Phox2
Biomedical Sciences
Online Access:https://dc.etsu.edu/etsu-works/8604
https://dc.etsu.edu/cgi/viewcontent.cgi?article=9868&context=etsu-works

Internet

https://dc.etsu.edu/etsu-works/8604
https://dc.etsu.edu/cgi/viewcontent.cgi?article=9868&context=etsu-works

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