Antidepressant- Like Actions of Inhibitors of Poly(ADP-Ribose) Polymerase in Rodent Models
The DNA base excision repair enzyme, poly(ADP-ribose) polymerase-1 (PARP1), is a multi-functional enzyme and a member of a subfamily of three PARPs that covalently build PAR polymers onto proteins to regulate their function. Drug inhibitors of PARPs have anti-cancer, anti-inflammatory, and neuroprot...
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Digital Commons @ East Tennessee State University
2017
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| Online Access: | https://dc.etsu.edu/etsu-works/8641 |