Chemical Complementation: A Genetic Selection System in Yeast for Drug Discovery, Protein Engineering, and for Deciphering and Assembling Biosynthetic Pathways
Chemical complementation is a general system for detecting protein-small molecule interactions, and linking that interaction to genetic selection. In this chemical complementation system, the interaction of a nuclear receptor and a ligand is essential for yeast survival. In first generation chemic...
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Format: | Others |
Language: | en_US |
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Georgia Institute of Technology
2006
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Online Access: | http://hdl.handle.net/1853/11637 |