Chemical Complementation: A Genetic Selection System in Yeast for Drug Discovery, Protein Engineering, and for Deciphering and Assembling Biosynthetic Pathways

Chemical complementation is a general system for detecting protein-small molecule interactions, and linking that interaction to genetic selection. In this chemical complementation system, the interaction of a nuclear receptor and a ligand is essential for yeast survival. In first generation chemic...

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Bibliographic Details
Main Author: Azizi, Bahareh
Format: Others
Language:en_US
Published: Georgia Institute of Technology 2006
Subjects:
Online Access:http://hdl.handle.net/1853/11637