Engineering Protein Molecular Switches To Regulate Gene Expression with Small Molecules

Small molecule dependent molecular switches that control gene expression are important tool in understanding biological cellular processes and for regulating gene therapy. Nuclear receptors are ligand activated transcription factors that have been engineered to selectively respond to synthetic ligan...

Full description

Bibliographic Details
Main Author: Rohatgi, Priyanka
Published: Georgia Institute of Technology 2008
Subjects:
Online Access:http://hdl.handle.net/1853/19852