The role of peroxiredoxins as mechanosensitive antioxidants in endothelial cells

Endothelial cells (EC) exposed to oscillatory shear stress (OS) experience oxidative stress as a signature of atherosclerosis. Conversely, unidirectional laminar shear stress (LS) reduces reactive oxygen species (ROS) levels and inflammatory responses. Peroxiredoxins (PRX) are antioxidant enzymes...

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Bibliographic Details
Main Author: Mowbray, Amy Leigh
Published: Georgia Institute of Technology 2008
Subjects:
Online Access:http://hdl.handle.net/1853/24779