Engineering a better receptor: characterization of retinoid x receptor alpha and functional variants

Engineering a better receptor: characterization of retinoid x receptor alpha and functional variants

The human retinoid X receptor alpha (hRXRalpha) is a member of the nuclear receptor super-family of ligand-activated transcription factors. The Doyle laboratory has previously engineered a variety of functional hRXRalpha variants that activate gene expression in response to synthetic ligands (LG335...

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Bibliographic Details
Main Author: Watt, Terry J.
Published: Georgia Institute of Technology 2009
Subjects:
Ligand binding
Protein engineering
Oligomerization
Thermal denaturation
Retinoid X receptor
Retinoids
Nuclear receptors (Biochemistry)
Ligand binding (Biochemistry)
DNA
Online Access:http://hdl.handle.net/1853/26647

Internet

http://hdl.handle.net/1853/26647

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