Study of serine palmitoyltransferase and de novo synthesis of sphingolipids

We have studied the molecular and biological consequences of overexpression of serine palmiotyltransferase (SPT) using HEK293 cells stably transfected with SPTLC1 and SPTLC2 (termed "SPT1/2 cells"). The effects of the elevated SPT activity were analyzed by liquid chromatography, electrospr...

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Bibliographic Details
Main Author: Wei, Jia
Published: Georgia Institute of Technology 2009
Subjects:
Online Access:http://hdl.handle.net/1853/28095