Study of serine palmitoyltransferase and de novo synthesis of sphingolipids
We have studied the molecular and biological consequences of overexpression of serine palmiotyltransferase (SPT) using HEK293 cells stably transfected with SPTLC1 and SPTLC2 (termed "SPT1/2 cells"). The effects of the elevated SPT activity were analyzed by liquid chromatography, electrospr...
Main Author: | |
---|---|
Published: |
Georgia Institute of Technology
2009
|
Subjects: | |
Online Access: | http://hdl.handle.net/1853/28095 |