Extending chemical complemenation to bacteria and furthering nuclear receptor based protein engineering and drug discovery
Nuclear receptors (NRs) are modular ligand-activated transcription factors that control a broad range of physiological processes by regulating the expression of essential genes involved in cell physiology, differentiation, and metabolism. These receptors are implicated in a number of diseases and d...
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Georgia Institute of Technology
2009
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| Online Access: | http://hdl.handle.net/1853/29652 |