Small molecule recognition of homopurine nucleic acid structures
The thesis topic entitled above involves the use of small molecules as a general means to drive nucleic acid assembly and structural transitions. We have shown that coralyne, a crescent-shaped small molecule, can assemble homo-adenine DNA and RNA sequences into anti-parallel duplexes at neutral pH,...
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Georgia Institute of Technology
2009
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| Online Access: | http://hdl.handle.net/1853/29739 |