Small molecule recognition of homopurine nucleic acid structures

The thesis topic entitled above involves the use of small molecules as a general means to drive nucleic acid assembly and structural transitions. We have shown that coralyne, a crescent-shaped small molecule, can assemble homo-adenine DNA and RNA sequences into anti-parallel duplexes at neutral pH,...

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Bibliographic Details
Main Author: Persil Cetinkol, Ozgul
Published: Georgia Institute of Technology 2009
Subjects:
Online Access:http://hdl.handle.net/1853/29739