Study of early signaling events in T cell activation enabled through a modular and multi-time point microfluidic device

Binding of the antigen receptor on T cells initiates a rapid series of signaling events leading to an immune response. To fully understand T cell mediated immunity, underlying regulatory properties of the receptor network must be understood. Monitoring dynamic protein signaling events allows for net...

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Bibliographic Details
Main Author: Rivet, Catherine Aurelie
Published: Georgia Institute of Technology 2010
Subjects:
Online Access:http://hdl.handle.net/1853/31674