The force regulation on binding kinetics and conformations of integrin and selectins using a bio-membrane force probe
Cell adhesion plays an important role in inflammation and immunological responses. Adhesion molecules (e.g., selectins and integrins) are key modulators in mediating these cellular responses, such as leukocyte trafficking under shear stress. In this thesis, we use a bio-membrane force probe (BFP) to...
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Georgia Institute of Technology
2010
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| Online Access: | http://hdl.handle.net/1853/33814 |