Characterization of the role of acid ceramidase in adrenocortical steroid hormone biosynthesis

Characterization of the role of acid ceramidase in adrenocortical steroid hormone biosynthesis

Sphingolipids modulate multiple cellular functions, including steroid hormone biosynthesis. Sphingosine is an antagonist ligand for the nuclear receptor steroidogenic factor 1 (SF-1), which is the primary transcriptional regulator of most steroidogenic genes. Furthermore, sphingosine-dependent repre...

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Bibliographic Details
Main Author: Lucki, Natasha Chrystman
Published: Georgia Institute of Technology 2012
Subjects:
Steroidogenic factor 1
Acid ceramidase
Sphingolipid
Adrenal gland
Cortisol
Sphingosine
Adrenal cortex
Adrenocortical hormones
Steroid hormones
Glycosphingolipids
Online Access:http://hdl.handle.net/1853/42804

Internet

http://hdl.handle.net/1853/42804

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