The role of vinculin in the cell adhesion strengthening process

Cell adhesion to extracellular matrices (ECM) is essential to numerous physiological and pathological processes. Cell adhesion is initiated by binding of the transmembrane integrin family of receptors to an ECM ligand such as fibronectin (FN). Once bound, integrins cluster together and form focal...

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Bibliographic Details
Main Author: Dumbauld, David W
Published: Georgia Institute of Technology 2012
Subjects:
Online Access:http://hdl.handle.net/1853/43729