Detection of frameshifts and improving genome annotation

Detection of frameshifts and improving genome annotation

We developed a new program called GeneTack for ab initio frameshift detection in intronless protein-coding nucleotide sequences. The GeneTack program uses a hidden Markov model (HMM) of a genomic sequence with possibly frameshifted protein-coding regions. The Viterbi algorithm nds the maximum likeli...

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Bibliographic Details
Main Author: Antonov, Ivan Valentinovich
Published: Georgia Institute of Technology 2013
Subjects:
Programmed frameshifting
Frameshifts
Pseudogenes
Indel mutations
Sequencing errors
Genomics
Markov processes
Online Access:http://hdl.handle.net/1853/45923

Internet

http://hdl.handle.net/1853/45923

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