Development of conformation-sensitive probes to fibronectin for ECM targeting and imaging of fibrosis
Fibronectin (Fn) is an adhesive extracellular matrix protein assembled by fibroblasts into fibrils within ECMs of developing and remodeling tissues. Fn is sensitive to mechanical forces exerted by contractile cells, and can alter its structural conformations in response to mechanical strain within F...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
Georgia Institute of Technology
2015
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/1853/53417 |