Understanding the relation between RNase H and retrotransposition activity in the context of the Aicardi-Goutieres syndrome
Ribonucleases (RNases) H1 and H2 are endonucleases that hydrolyze the RNA strand of RNA-DNA hybrids forming at the chromosomal level as well as extra-chromosomal hybrids. Extra-chromosomal RNA-DNA hybrids can frequently occur in cells as intermediate structures in the process of reverse transcriptio...
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Georgia Institute of Technology
2015
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| Online Access: | http://hdl.handle.net/1853/53997 |