A toolkit for analysis of gene editing and off-target effects of engineered nucleases
Several tools were developed to help researchers facilitate clinical translation of the use of engineered nucleases towards their disease gene of interest. Two major issues addressed were the inability to accurately predict nuclease off-target sites by user-friendly \textit{in silico} methods and th...
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Format: | Others |
Language: | en_US |
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Georgia Institute of Technology
2016
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Online Access: | http://hdl.handle.net/1853/54875 |