A toolkit for analysis of gene editing and off-target effects of engineered nucleases

Several tools were developed to help researchers facilitate clinical translation of the use of engineered nucleases towards their disease gene of interest. Two major issues addressed were the inability to accurately predict nuclease off-target sites by user-friendly \textit{in silico} methods and th...

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Bibliographic Details
Main Author: Fine, Eli Jacob
Other Authors: Bao, Gang
Format: Others
Language:en_US
Published: Georgia Institute of Technology 2016
Subjects:
Online Access:http://hdl.handle.net/1853/54875