Tetrahydrobiopterin Oxidation and Reactive Oxygen Species Contribute to H2O2-Induced Endothelial Nitric Oxide Synthase Dysfunction
An oxidative stress in the form of H2O2 exposure previously has been shown to cause a transient increase in NO??oduction and a chronic increase in eNOS protein levels. Nevertheless, oxidative stress can cause an uncoupling of catalytic activity resulting in decreased NO??d increased O2??roduction fr...
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| Format: | Others |
| Language: | en_US |
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Georgia Institute of Technology
2005
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| Online Access: | http://hdl.handle.net/1853/7111 |