Using Protein Design to Understand the Role of Electrostatic Interactions on Calcium Binding Affinity and Molecular Recognition

Calcium regulates many biological processes through interaction with proteins with different conformational, dynamic, and metal binding properties. Previous studies have shown that the electrostatic environment plays a key role in calcium binding affinity. In this research, we aim to dissect the con...

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Bibliographic Details
Main Author: Jones, Lisa Michelle
Format: Others
Published: Digital Archive @ GSU 2008
Subjects:
Online Access:http://digitalarchive.gsu.edu/chemistry_diss/16
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1015&context=chemistry_diss