Targeted Molecular MR Imaging of HER2 and EGFR Using De Novo Designed Protein Contrast Agents

The application of magnetic resonance imaging (MRI) to non-invasively assess disease biomarkers has been hampered by lack of desired contrast agents with high relaxivity, targeting capability, and optimized pharmacokinetics. We developed a novel MRI probe which targets HER2, a biomarker for various...

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Bibliographic Details
Main Author: Qiao, Jingjuan
Format: Others
Published: Digital Archive @ GSU 2011
Subjects:
MRI
Online Access:http://digitalarchive.gsu.edu/chemistry_diss/62
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1061&context=chemistry_diss