Conduits of Intratumor Heterogeneity: Centrosome Amplification, Centrosome Clustering and Mitotic Frequency

Conduits of Intratumor Heterogeneity: Centrosome Amplification, Centrosome Clustering and Mitotic Frequency

Tumor initiation and progression is dependent on the acquisition and accumulation of multiple driver mutations that acti­vate and fuel oncogenic pathways and deactivate tumor suppressor networks. This complex continuum of non-stochastic genetic changes in accompaniment with error-prone mitoses large...

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Bibliographic Details
Main Author: Pannu, Vaishali
Format: Others
Published: ScholarWorks @ Georgia State University 2014
Subjects:
Mitotic frequency
Intratumoral heterogeneity
Metastasis
Centrosome amplification
Online Access:http://scholarworks.gsu.edu/biology_diss/153
http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1158&context=biology_diss

Internet

http://scholarworks.gsu.edu/biology_diss/153
http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1158&context=biology_diss

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