Rational Design, Synthesis, and Evaluation of Inhibitors for the HIV-1 TAT Interacting Protein Tip60
The histone acetyltransferase protein, Tip60, has many important functions in epigenetic regulation of gene expression and DNA repair. Our objective is to design, synthesize, and evaluate potent inhibitors for Tip60. Full-length Tip60 (fl-Tip60) and catalytic domain of Tip60 (cat-Tip60) were express...
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| Format: | Others |
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ScholarWorks @ Georgia State University
2013
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| Online Access: | http://scholarworks.gsu.edu/biology_theses/46 http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1046&context=biology_theses |