Inhibitors of SecA as Potential Antimicrobial Agents

Inhibitors of SecA as Potential Antimicrobial Agents

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Protein translocation is essential for bacterial survival and the most important translocation mechanism in bacteria is the secretion (Sec) pathway. Thus targeting Sec pathway is a promising strategy for developing novel antibacterial therapeutics. We report the design, syntheses, mechanistic studie...

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Bibliographic Details
Main Author: Chaudhary, Arpana S
Format: Others
Published: ScholarWorks @ Georgia State University 2013
Subjects:
SecA inhibitors
Sec pathway inhibition
Thiouracil
1
2
4-Triazole
Novel antibacterial therapeutics
Protein translocation inhibition
Online Access:http://scholarworks.gsu.edu/chemistry_diss/77
http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1077&context=chemistry_diss

Internet

http://scholarworks.gsu.edu/chemistry_diss/77
http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1077&context=chemistry_diss

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