Using Molecular Dynamics to Elucidate the Mechanism of Cyclophilin

Cyclophilins are ubiquitous enzymes that are involved in protein folding, signal transduction, viral proliferation, oncogenesis, and regulation of the immune system. Cyclophilin A is the prototype of the cyclophilin family. We use molecular dynamics to describe the catalytic mechanism of cyclophilin...

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Bibliographic Details
Main Author: McGowan, Lauren
Format: Others
Published: ScholarWorks @ Georgia State University 2014
Subjects:
Online Access:http://scholarworks.gsu.edu/chemistry_diss/88
http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1091&context=chemistry_diss