Using Molecular Dynamics to Elucidate the Mechanism of Cyclophilin
Cyclophilins are ubiquitous enzymes that are involved in protein folding, signal transduction, viral proliferation, oncogenesis, and regulation of the immune system. Cyclophilin A is the prototype of the cyclophilin family. We use molecular dynamics to describe the catalytic mechanism of cyclophilin...
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ScholarWorks @ Georgia State University
2014
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Online Access: | http://scholarworks.gsu.edu/chemistry_diss/88 http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1091&context=chemistry_diss |