Exploring HIV Integrase 3’-processing Using Designed DNA Substrates and Structural Study of HIV DNA Hairpins
In the HIV viral integration procedure, 3’-processing of the viral DNA by the integrase enzyme is an essential first step which is followed by the integration of viral DNA into the host genome. In 3’-processing, the integrase cleaves the backbone of the DNA substrate on the 3’ end of a conserved CA...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
ScholarWorks @ Georgia State University
2016
|
| Subjects: | |
| Online Access: | http://scholarworks.gsu.edu/chemistry_theses/96 http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1097&context=chemistry_theses |