Characterization of the roles of yeast nuclear exosome cofactor TRAMP complex in pre-mRNA splicing
In budding yeast, the Trf4/5p-Air1/2p-Mtr4p polyadenylation (TRAMP) complex recognizes unwanted RNA transcripts in the nucleus and then targets them to the nuclear exosome for rapid degradation, constituting an important pathway of nuclear RNA quality control. Each pre-mRNA splicing event unavoidabl...
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Language: | English |
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The University of Hong Kong (Pokfulam, Hong Kong)
2014
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Online Access: | http://hdl.handle.net/10722/193522 |