Two-stage adaptive designs in early phase clinical trials

The primary goal of clinical trials is to collect enough scientific evidence for a new intervention. Despite the widespread use of equal randomization in clinical trials, response-adaptive randomization has attracted considerable interest in terms of ethical concerns. In this thesis, delayed respons...

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Bibliographic Details
Main Authors: Xu, Jiajing, 徐佳静
Language:English
Published: The University of Hong Kong (Pokfulam, Hong Kong) 2014
Subjects:
Online Access:http://hdl.handle.net/10722/202252