A apoptose induzida pelo anti-inflamatório não esteróide salicilato de sódio requer a participação da proteína cinase gcn2 e o envolvimento de vias do estresse do retículo endoplasmático

=== Salicylates are non-steroidal anti-inflammatory drugs with the well-known ability to inhibit cyclooxygenase activity, the key enzyme in prostaglandin biosynthesis. The salicylates also induce the phosphorylation of the alpha-subunit of eukaryotic translation initiation factor (eiF2 alpha). Unde...

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Bibliographic Details
Main Author: Solange Henschke Lima Gentz
Other Authors: Aristobolo Mendes da Silva
Format: Others
Language:Portuguese
Published: Universidade Federal de Minas Gerais 2011
Online Access:http://hdl.handle.net/1843/BUOS-8UBJNE