Síntese, avaliação farmacológica e estudos computacionais de dímeros de tacrina
=== This work presents the synthesis of fifteen new tacrine dimers and results for Ki, IC50, kinetic mechanism and molecular docking analysis in relation to cholinesterases; and the assessment results of the antitumorigenic activity of these new molecules for ten representative cell lines as well a...
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Format: | Others |
Language: | Portuguese |
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Universidade Federal de Minas Gerais
2014
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Online Access: | http://hdl.handle.net/1843/SFSA-9JWRFZ |