Síntese, avaliação farmacológica e estudos computacionais de dímeros de tacrina 

=== This work presents the synthesis of fifteen new tacrine dimers and results for Ki, IC50, kinetic mechanism and molecular docking analysis in relation to cholinesterases; and the assessment results of the antitumorigenic activity of these new molecules for ten representative cell lines as well a...

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Bibliographic Details
Main Author: Roney Anderson Nascimento de Aquino
Other Authors: Angelo de Fatima
Format: Others
Language:Portuguese
Published: Universidade Federal de Minas Gerais 2014
Online Access:http://hdl.handle.net/1843/SFSA-9JWRFZ