Parkinson's disease : experimental in vitro model validation and the potential role of cofilin-1 in the pathophysiological mechanisms

The dopaminergic neurodegeneration in the substantia nigra pars compacta (SNpc) is responsible for the marked motor impairment observed in Parkinson's disease (PD). However, the molecular mechanisms underlying this are not completely understood. Since by the time of diagnosis, 50-70% of the dop...

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Bibliographic Details
Main Author: Lopes, Fernanda Martins
Other Authors: Klamt, Fabio
Format: Others
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10183/159503