Mechanism of RAG Regulation During Its Physiological and Pathological Functions in Lymphoid Cells
RAGs (Recombination Activating Genes) are responsible for generation of antigen receptor diversity in case of B-cells and T-cells, through the process of combinatorial joining of different V (variable), D (diversity) and J (joining) gene segments. Each of these segments are flanked by recombination...
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Language: | en_US |
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2018
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Online Access: | http://etd.iisc.ernet.in/2005/3944 http://etd.iisc.ernet.in/abstracts/4822/G27195-Abs.pdf |