Mechanism Of RAG Action As A Structure-Specific Nuclease : Implications In Genomic Instability In Lymphoid Cells

Mechanism Of RAG Action As A Structure-Specific Nuclease : Implications In Genomic Instability In Lymphoid Cells

Recombination Activating Genes (RAGs) orchestrate the process called V (D) J recombination, which enables the vertebrate adaptive immune system to specifically recognize millions of antigens. During this recombination process, V (variable), D (diversity) and J (joining) gene segments of antibody (B...

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Bibliographic Details
Main Author: Naik, Abani Kanta
Other Authors: Raghavan, Sathees C
Language:en_US
Published: 2013
Subjects:
Lymphoid Cells
Genomes - Instability
Nuclease
RAG
Recombination Activating Genes (RAGs)
Structure-specific Nuclease
DNA Substrates
Biochemical Genetics
Online Access:http://etd.iisc.ernet.in/handle/2005/2127
http://etd.ncsi.iisc.ernet.in/abstracts/2731/G25008-Abs.pdf

Internet

http://etd.iisc.ernet.in/handle/2005/2127
http://etd.ncsi.iisc.ernet.in/abstracts/2731/G25008-Abs.pdf

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