Mechanism of Abrin-Induced Apoptosis and Insights into the Neutralizing Activity of mAb D6F10
Abrin is a potent toxin obtained from the seeds of Abrus precatorius. It is a heterodimeric glycoprotein consisting of an A and a B subunit linked together by a disulfide bond. The toxicity of the protein comes from the A subunit harboring RNA-N-glycosidase activity which cleaves the glycosidic bond...
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| Language: | en_US |
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2017
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| Online Access: | http://hdl.handle.net/2005/2787 http://etd.ncsi.iisc.ernet.in/abstracts/3654/G26623-Abs.pdf |