The Effect of Substituents and Solvents on the Deiodination Reactions of Thyroid Hormones by Iodothyronine Deiodinase Mimics

Thyroid hormones (THs; T4 and T3), secreted from thyroid gland, play an important role in human growth and development. T3 (3,5,3′-triiodothyronine) is the active hormone and the conversion of T4 (3,3′,5,5′-tetraiodothyronine) to T3 in cells is mediated by iodothyronine deiodinases enzymes (DIOs). D...

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Bibliographic Details
Main Author: Raja, K
Other Authors: Mugesh, G
Language:en_US
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/2005/2870
http://etd.ncsi.iisc.ernet.in/abstracts/3739/G28225-Abs.pdf