The protein tyrosine phosphate, SHP2, functions in multiple cellular compartments in FLT3-ITD+ Leukemia
Indiana University-Purdue University Indianapolis (IUPUI) === FMS-like tyrosine receptor kinase-internal tandem duplications (FLT3-ITDs) are the most frequent deleterious mutations found in acute myeloid leukemia (AML) and portend a poor prognosis. Currently, AML patients typically achieve disease...
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| Language: | en_US |
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2016
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| Online Access: | http://hdl.handle.net/1805/10476 |