Mutant P53 in pre-leukemic hematopoietic stem cells and the pathogenesis of Myelodysplastic Syndrome

Indiana University-Purdue University Indianapolis (IUPUI) === Myelodysplastic syndrome (MDS) is a clonal disease arising from mutated hematopoietic stem cells (HSCs). MDS stem cells originate from pre-leukemic HSCs, which have enhanced competitive advantage over wild-type (WT) HSCs but normal dif...

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Bibliographic Details
Main Author: Chen, Sisi
Other Authors: Liu, Yan
Language:en_US
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/1805/16283
https://doi.org/10.7912/C2MW81