Investigating the molecular mechanism of phospholamban regulation of the Ca²-pump of cardiac sarcoplasmic reticulum
Indiana University-Purdue University Indianapolis (IUPUI) === The Ca2+ pump or Ca2+-ATPase of cardiac sarcoplasmic reticulum, SERCA2a, is regulated by phospholamban (PLB), a small inhibitory phosphoprotein that decreases the apparent Ca2+ affinity of the enzyme. We propose that PLB decreases Ca2+ a...
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| Language: | en_US |
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2011
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| Online Access: | http://hdl.handle.net/1805/2516 |