mTORC1 contributes to ER stress induced cell death

mTORC1 contributes to ER stress induced cell death

Indiana University-Purdue University Indianapolis (IUPUI) === Patients with the genetic disorder tuberous sclerosis complex (TSC) suffer from neoplastic growths in multiple organ systems. These growths are the result of inactivating mutations in either the TSC1 or TSC2 tumor suppressor genes, which...

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Bibliographic Details
Main Author: Babcock, Justin Thomas
Other Authors: Quilliam, Lawrence
Language:en_US
Published: 2014
Subjects:
Vacuole
ER stress
TSC
LAM
Bortezomib
Rapamycin
Tuberous sclerosis > Research
Endoplasmic reticulum > Pathophysiology
Phosphorylation
Stress (Physiology)
Messenger RNA
Antineoplastic agents
Proteolytic enzymes
Cellular control mechanisms > Research
Apoptosis
Online Access:http://hdl.handle.net/1805/3810

Internet

http://hdl.handle.net/1805/3810

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