Identification and characterization of altered mitochondrial protein acetylation in Friedreich's ataxia cardiomyopathy

Identification and characterization of altered mitochondrial protein acetylation in Friedreich's ataxia cardiomyopathy

Indiana University-Purdue University Indianapolis (IUPUI) === Friedreich’s Ataxia (FRDA) is a rare and poorly understood autosomal recessive disease caused by a pathological deficiency of the mitochondrial protein frataxin. Patients suffer neurodegeneration, ataxia, diabetes, and heart failure. In a...

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Bibliographic Details
Main Author: Wagner, Gregory Randall
Other Authors: Payne, R. Mark
Language:en_US
Published: Hindawi Publishing Corporation and Oxford Journals and SAGE Journals 2014
Subjects:
Friedreich's ataxia > Research > Methodology > Analysis
Mitochondrial pathology > Research > Methodology
Acetylation
Myocardium > Diseases
Nervous system > Degeneration
Heart failure
Metabolism > Regulation
Histone deacetylase > Research
Heart > Pathophysiology
Proteomics
Mitochondrial membranes
Online Access:http://hdl.handle.net/1805/4209

Internet

http://hdl.handle.net/1805/4209

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