Aromatase inhibitors produce hypersensitivity in experimental models of pain : studies in vivo and in isolated sensory neurons

Aromatase inhibitors produce hypersensitivity in experimental models of pain : studies in vivo and in isolated sensory neurons

Indiana University-Purdue University Indianapolis (IUPUI) === Aromatase inhibitors (AIs) are the current standard of care for the treatment of hormone receptor positive breast cancer in postmenopausal women. Nearly one-half of patients receiving AI therapy develop musculoskeletal toxicity that is ch...

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Bibliographic Details
Main Author: Robarge, Jason Dennis
Other Authors: Flockhart, David A.
Language:en_US
Published: 2015
Subjects:
aromatase
aromatase inhibitor
musculoskeletal pain
neuropeptide
nociception
sensory neuron
behavior
Aromatase > Therapeutic use > Research
Aromatase > Inhibitors > Side effects
Aromatase > Antagonists > Therapeutic use
Estrogen > Antagonists > Therapeutic use
Breast > Cancer > Chemotherapy
Breast > Cancer > Hormone therapy
Drugs > Side effects
Nociceptors > Behavior
Menopause > Hormone therapy > Evaluation
Musculoskeletal system > Abnormalities > Research
Myalgia
Neuropeptides > Research
Sensory neurons > Research > Methodology > Evaluation
Nociceptors > Physiology
Rats as laboratory animals > Nervous system
Online Access:http://hdl.handle.net/1805/6056

Internet

http://hdl.handle.net/1805/6056

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