Role of S6K1 in regulating self-renewal of hematopoietic stem cells and propagatoin of leukemia

Indiana University-Purdue University Indianapolis (IUPUI) === The development and function of hematopoietic stem cells (HSCs) is regulated by numerous signaling pathways including Akt-mechanistic target of rapamycin complex1 (mTORC1) pathway. Dysregulation of this pathway results in impaired HSC fun...

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Bibliographic Details
Main Author: Ghosh, Joydeep
Other Authors: Kapur, Reuben
Language:en_US
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/1805/9782