Role of S6K1 in regulating self-renewal of hematopoietic stem cells and propagatoin of leukemia
Indiana University-Purdue University Indianapolis (IUPUI) === The development and function of hematopoietic stem cells (HSCs) is regulated by numerous signaling pathways including Akt-mechanistic target of rapamycin complex1 (mTORC1) pathway. Dysregulation of this pathway results in impaired HSC fun...
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Language: | en_US |
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2016
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Online Access: | http://hdl.handle.net/1805/9782 |