A biophysical study of intranuclear herpes simplex virus type 1 DNA during lytic infection

Herpes Simplex Virus Type 1 (HSV-1) establishes latent infections in neurons in vivo and lytic infections in epithelial cells and fibroblasts. During latent infections, HSV-1 transcription is restricted and the genomes are not replicated. Latent HSV-1 genomes are chromatinized, such that digestion w...

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Bibliographic Details
Main Author: Lacasse, Jonathan J
Other Authors: Schang, Luis (Biochemistry and Medical Microbiology and Immunology)
Format: Others
Language:en
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10048/1359